Annexin A6 mediates calcium-dependent exosome secretion during plasma membrane repair.
Williams JK*,Ngo JM*, Lehman IM, Schekman R. (*equal contribution) Elife. 2023 May 19;12:e86556. doi: 10.7554/eLife.86556. PMID: 37204294.
Syncytin-mediated open-ended membrane tubular connections facilitate the intercellular transfer of cargos including Cas9 protein.
Zhang C, Schekman R. Elife. 2023 Mar 10;12:e84391. doi: 10.7554/eLife.84391. PMID: 36896791.
Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers.
Wu S, Hernandez Villegas NC, Sirkis DW, Thomas-Wright I, Wade-Martins R, Schekman R. Elife. 2023 Jan 10;12:e85837. doi: 10.7554/eLife.85837. PMID: 36626307.
Extracellular vesicles from neurons promote neural induction of stem cells through cyclin D1.
Song L, Tian X, Schekman R. J Cell Biol. 2021 Sep 6;220(9):e202101075. doi: 10.1083/jcb.202101075. PMID: 34309628.
Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes.
Temoche-Diaz MM, Shurtleff MJ, Nottingham RM, Yao J, Fadadu RP, Lambowitz AM, Schekman R. Elife. 2019 Aug 22;8:e47544. doi: 10.7554/eLife.47544. PMID: 31436530
Fatty-acid binding protein 5 modulates the SAR1 GTPase cycle and enhances budding of large COPII cargoes.
Melville D, Gorur A, Schekman R. Mol Biol Cell. 2019 Feb 1;30(3):387-399. doi: 10.1091/mbc.E18-09-0548. PMID: 30485159.
TANGO1 and SEC12 are copackaged with procollagen I to facilitate the generation of large COPII carriers.
Yuan L, Kenny SJ, Hemmati J, Xu K, Schekman R. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12255-E12264. doi: 10.1073/pnas.1814810115. PMID: 30545919.
Extracellular Vesicles and Cancer: Caveat Lector.
Shurtleff MJ, Temoche-Diaz MM, Schekman R. Annu Rev Cancer Bio. 2018 2:1, 395-411. doi: 10.1146/annurev-cancerbio-030617-050519.
Unconventional secretion of FABP4 by endosomes and secretory lysosomes.
Villeneuve J, Bassaganyas L, Lepreux S, Chiritoiu M, Costet P, Ripoche J, Malhotra V, Schekman R. J Cell Biol. 2018 Feb 5;217(2):649-665. doi: 10.1083/jcb.201705047. PMID: 29212659.
Broad role for YBX1 in defining the small noncoding RNA composition of exosomes.
Shurtleff MJ*, Yao J*, Qin Y, Nottingham RM, Temoche-Diaz MM, Schekman R#, Lambowitz AM#. (*equal contribution, #co-corresponding authors) Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E8987-E8995. doi: 10.1073/pnas.1712108114. PMID: 29073095.